Best Nootropic Pills That Work: Top Recommended Supplements

Using a nootropic supplement to improve the brain is pretty standard, helping consumers everywhere to enhance memory and cognition. Though there are many different formulas today, picking the right product can help consumers feel smarter and work better.

Each one works differently. While some products help users improve blood flow to oxygenate the brain, others use herbal extracts, vitamins, minerals, and plants.

Consumers of all ages and types of work can benefit from nootropics. However, it is necessary to determine the best product to suit these needs. In this guide, consumers will learn about today’s top remedies for brain health.

The Top 33 Nootropic Brain Booster Supplements

The following 33 nootropic formulas perform above the rest based on strict criteria:

  • SANE Vitaae
  • Mind Lab Pro
  • Nuzena Neuro Focus +
  • NooBru
  • Nootrogen
  • Ageless Brain
  • Onnit Alpha Brain
  • Hunter Focus
  • Qualia Mind
  • Performance Lab Mind
  • Vital Plan Brain Boost
  • NaturalCell NeuroActiv6
  • Synapse XT
  • NooCube
  • Natural Stacks NeuroFuel
  • UpWellness Mind & Mood
  • PureEssence BrainEssence
  • PureHealth Research Ageless Brain
  • Brain C-13
  • Cymbiotika Golden Mind
  • Elm & Rye Nootropics
  • CogniBiotics
  • Amy Myers MD NeuroLive
  • Neuro
  • OptiMind
  • Youthful Brain
  • Oweli Neuro
  • ReMind Solution
  • Brain Pill
  • ProMind Complex
  • Memory Hack
  • MemoSurge
  • Memo Defend

To learn about what all of these products offer, read below.

SANE Vitaae


SANE Vitaae focuses on bringing users clearer focus and mental clarity with their daily cognitive efforts. It improves the user’s mood by regulating the nervous system, making it easier to concentrate on what’s important.

The use of herbal extracts and vitamins provides antioxidants that can combat inflammation in the brain. SANE Vitaae includes folate, vitamin D, acetyl L-carnitine, CoQ10, and other familiar ingredients in the nootropic space to create this effect. According to the lab tests at SANE Laboratories, this formula could increase the brain’s energy use by 13.6%.

For a bottle of 45 capsules, the total cost is $47. Users will need to take three capsules to get the desired effects each day. If the user is unhappy with the results, they have one year to get a full refund.

Mind Lab Pro


Mind Lab Pro helps consumers improve their mental sharpness, supporting the growth of healthy brain cells that can ultimately improve mental stimulation. It also helps with brain function. As one of the most popular products in the nootropic industry, users can get nourishment from 11 ingredients proven to boost brain health. It is one of the top-rated options for consumers in the entire industry, boasting the support of a medical advisory board.

Consumers get all the support that the creators can muster with many ingredients. The ingredients include many plants and herbal extracts, like Rhodiola Rosea, Maritime pine bark extract, and Bacopa Monnieri.

To get a bottle of 60 capsules, the total cost of Mind Lab Pro is $69. Taking two pills a day provides users with the promised benefits.

Nuzena Neuro Focus +


Nuzena Neuro Focus + ensures that users promote better cognitive function and increase their mental performance. As it encourages better mental energy, consumers will focus more easily. The entire recipe is condensed into a proprietary blend that includes ingredients like green tea extract, bilberry fruit extract, amino acid, and other elements to achieve these effects.

The nutritional benefits offered by this nootropic stack are highly affordable. A bottle of 60 capsules costs $30. Consumers that want to save on their purchase can order three bottles for $60, giving them the equivalent of one free bottle. Users will need to take two capsules a day to get the brain benefits.



NooBru offers a powder instead of a capsule, blending the power of alpha GPC, vitamin B5, L-theanine, ashwagandha, Huperzine A, and choline bitartrate. Consumers like this formula because it offers better mental energy and focus, contributing to overall better brain function. It is one of the few products on this list that claims to help regenerate damaged brain cells, which is why it is marketed to older adults at risk of dementia, Alzheimer’s, and other age-related brain issues.

To prepare this powder, blend a scoop of the supplement with any beverage for daily consumption. Users can get a canister of 20 servings for $55, and all purchases are covered with a 100% risk-free guarantee.



Nootrogen deals with the user’s stress, significantly impacting their brain health. It promotes healthier energy levels, greater focus, and improved balance of the natural chemicals in the brain. The formula is unique since it includes DMAE, amino acids, glutamic acid, and L-tyrosine, which isn’t often seen in nootropic remedies.

Users need to take two capsules a day for the advertised benefits. For a bottle of 60 pills, the total cost is $30.

Ageless Brain


Ageless Brain has many familiar ingredients for nootropic formulas, including Bacopa Monnieri, cat’s claw, cacao, cinnamon, dragon’s blood, guayusa, and others. This formula is primarily marketed towards older consumers, helping heal the damage with age and improving mental function. It stimulates the growth of new brain cells while improving the user’s cognitive processing speed.

To get 60 capsules (which is 30 2-capsule doses), the total cost is $55. Every purchase comes with a one-year satisfaction guarantee, giving users a refund if needed.

Onnit Alpha Brain


Onnit Alpha Brain helps users improve memory retention and improve their brain health. It includes ingredients like cat’s claw, oat straw, Bacopa Monnieri, Huperzia Serrata, and other necessary amino acids to improve cognition. Ultimately, it supports mental performance and cognitive function, offering a risk-free money-back guarantee.

Part of the reason that this formula has earned so much popularity is that Joe Rogan endorses it. Rogan, the brand’s co-owner, ensured that the formula went through clinical research. Most companies don’t go through the effort to test their particular remedy, focusing instead on ingredients that already come with their research.

For a 90-capsule bottle, the total cost is $35. Users need to take three capsules daily to get results.

Hunter Focus


Hunter Focus combines Bacopa Monnieri, Maritime pine bark extract, and phosphatidylserine. Consumers get a version of a nootropic supplement that is already relatively familiar with these ingredients. It improves memory and focus while encouraging a more positive mood from customers. It also improves brain energy and supports the user’s creativity. Developed by Roar Nutrition, this remedy can also eliminate mental fatigue.

To get 120 capsules in one bottle, the total cost is $60, making it one of the pricier options on the list. Users need to take four pills a day to get the benefits.

Qualia Mind


Qualia Mind is made of artichoke leaf extract, taurine, citicoline, Mucuna pruriens, theobromine, and phosphatidylserine (among others), and it triggers restoration of the natural chemicals in the brain. It helps consumers fight back against the symptoms associated with cognitive decline, helping to improve the user’s mental performance. It also supports improved focus.

A bottle of 154 capsules costs $59, giving the user enough to last through 77 servings. Users are covered with a 100-day money-back guarantee.



Mind, a remedy by Performance Lab, helps users increase brain energy by over 13%, ensuring that users get the improved mental performance they need.

To get 30 capsules, the total cost is $69. Users will need two pills every day to get the results. A 30-day return policy covers everything.

Brain Boost


Brain Boost helps users improve their cognitive function by increasing blood flow, helping the brain get the nourishment it needs. The use of ginkgo Biloba, ashwagandha, cat’s claw, lion’s mane, and Bacopa Monnieri are all necessary to achieve this effect. It also improves the user’s memory for better mental clarity and enhances focus and immunity. All of the ingredients benefit the user, which means they can also count on less stress and a better mood. It even promotes a healthier gut.

For 120 capsules in one bottle, the total cost is $48. Users need four pills a day to get the benefits.



NeuroActiv6 focuses on using patented ingredients to help make a difference for consumers. With NeuroFactor (coffee fruit), Sensoril (Withania somnifera), Activin (grape seed), and Cognizin (citicoline), they can promote better BDNF levels in the brain, reducing stress and balancing cortisol levels.

For 30 servings, the total cost is $46. Users will have to portion out the powder with the included scoop to get the benefits. However, all orders are covered by a 60-day money-back guarantee.

Synapse XT


Synapse XT focuses on helping older adults who deal with hearing issues, memory loss, and a lack of focus. It reduces mental fatigue as it improves mental performance and cognition. This remedy is particularly beneficial to individuals who want to combine hearing and cognitive issues.

To get these results, users get the support of rosemary, magnesium, potassium, B vitamins, garlic, hibiscus, and hawthorn berry. Users only need two capsules a day, and each bottle offers enough pills to last through the next 20 days.

The total cost of one bottle is $69.

NooCube Brain Productivity


NooCube Brain Productivity provides users with improvement to their brain function, better mental processing speed, and improved mood. There is no caffeine in this formula, but users get a plethora of herbal extracts, plant extracts, and other essential nutrients.

For 60 capsules, the total cost is $60, giving users enough 2-capsule doses to last the whole month. All orders come with a 60-day money-back guarantee.



NeuroFuel helps consumers improve how well they can concentrate on the task by improving nerve growth factors. It improves brain function and focus, using ingredients like forskolin, acetyl L-carnitine, vitamin B6, L-phenylaniline, and artichoke extract. Interestingly, NeuroFuel offers a certain level of transparency because it shows all of the sources of its ingredients on the blockchain.

Consumers will get 45 capsules in every bottle, which costs $30. Taking three pills a day is enough to get the support needed.

Mind & Mood


Mind & Mood helps users eliminate stress and anxiety, giving them more space to focus on what’s important. The formula’s use of ingredients like 5-HTP, GABA, saffron, L-theanine, and Rhodiola Rosea help the brain cells to signal each other more efficiently, making the individual think faster and concentrate better. This entire formula is made as a collaboration between two doctors – by Dr. Joshua Levitt and Dr. Amanda Levitt – which is not something that many products can boast.

To get a 90-capsule bottle, the total cost of Mind & Mood is $57. Users need to take two capsules a day to get the results they hope for, though the company offers a money-back guarantee to anyone unsatisfied for the first 60 days.



BrainEssence helps consumers to improve their stress response due to the way that it can calm the mind and help users refocus. It enhances the user’s mood and brain function simultaneously, improving their mental performance. Consumers don’t have to worry about swallowing a large capsule instead of using a tablet.

Rather than hiding within a proprietary blend, consumers can see the exact amount of every ingredient that goes into BrainEssence. It includes Bacopa Monnieri, ashwagandha, and acetyl L-carnitine in the highest amounts, with lower Chinese club moss extract levels, Rhodiola Rosea, and amino acids.

Users need two tablets each day to get results. For a 30-tablet bottle, the total cost is $30, and it comes with a 90-day refund policy.

PureHealth Research Ageless Brain


Ageless Brain by PureHealth Research provides users with GABA, caffeine, huperzine A and B vitamins to support their cognition. This remedy is often used as a solution for individuals who want to ease their anxiety to promote better focus and improve their memory. Consumers can also feel confident in using this remedy for the support provided by Dr. Holly Lucille.

The total cost of a 30-capsule bottle is $44, and users only need one capsule a day to make a difference. The formula comes with a one-year money-back guarantee for anyone unhappy with the results.

Brain C-13


Brain C-13 combines DMAE, Rhodiola Rosea extract, rosemary leaf, turmeric, ginkgo leaf, huperzine A, and phosphatidylserine to create a remedy that increases the user’s brain function. With three capsules a day, most users experience better concentration and focus because their stress drastically reduces.

Created by Zenith Labs, consumers can see every ingredient on the label with their dosage, ensuring that they know what they are getting. The company has its medical advisory board to ensure this product delivers on its promises.

For a 90-capsule bottle, the cost is $49, which is backed by a six-month return policy.

Cymbiotika Golden Mind


Cymbiotika Golden Mind focuses on promoting better blood flow to reduce brain fog. Without this foggy feeling, users improve their cognitive performance and provide an environment conducive to brain cell growth.

To get these effects, consumers will use 14 pumps of the liquid tincture, which contains amino acids, lion’s mane mushroom powder extract, organic phosphatidylcholine, and L-theanine. The bottle comes with enough liquid to make 30 servings, and it is the only product on this list available as a liquid.

One bottle costs $50.

Elm & Rye Nootropics


Elm & Rye Nootropics includes GABA, Bacopa Monnieri, Alpha GPC, L-theanine, L-tyrosine, phosphatidylserine, and B vitamins to support the memory and retain new information. With this mental energy and better cognitive function, users can improve their productivity and increase stamina through even mundane mental activities. It even includes a slight caffeine boost, giving users the same stimulation that they would experience with 2-3 cups of coffee.

Users need to take two capsules each day to get the desired results. With a 60-capsule bottle, users can expect to pay $85.



CogniBiotics has two main components to the remedy – the Shen Bu Xin San formula and the Chaihu-Shugan-San formula. These two proprietary blends are unique to CogniBiotics, helping with mental clarity, memory retention, learning, concentration, and overall brain health.

Instead of focusing entirely on the brain, this formula recognizes gut health’s role in brain development and cognition. With 17 ingredients, adaptogenic herbs, and nootropic ingredients, users get help with cognitive function, stress, and more through a healthier gut.

For a 60-capsule bottle, the total cost is $62, covered for up to one year with the return policy.

Amy Myers MD NeuroLive


Amy Myers MD NeuroLive supports the user’s brain health and improves natural cognition. The plethora of ingredients – including Mucuna Pruriens, Ginkgo Biloba, N-acetyl tyrosine, L-theanine, and Bacopa Monnieri – improves the user’s brain cell development, purging the body of toxins. Without these toxins, inflammation subsides, and the brain can thrive. Users will need to take two capsules a day to get the full benefits.

With a 90-day return policy, the total cost of this formula is $49.97. Plus, users won’t have to pay a cent for shipping.



Neuro helps consumers boost their mental energy without feeling jittery by offering natural caffeine, B vitamins, and L-theanine. The recipe may seem a bit simple, but users will find that they don’t need much to enhance focus and brain function. Instead of a capsule or a tincture, Neuro is offered as a stick of gum, and users only need to chew one piece a day for the therapeutic support they hope for.

This brand has three different products – Energy & Focus, Calm & Clarity, and Ideal State. One package of the Neuro gum starts at $21.



OptiMind focuses primarily on bringing users Bacopa Monnieri as the catalyst for brain health changes. Users will notice better mental clarity and physical performance with this main ingredient. Users need two capsules a day to get these effects.

The total cost of this formula is $30.

Youthful Brain


Youthful Brain includes a few essential nutrients – vitamin B12, huperzine A, and Bacopa Monnieri. Consumers improve their mental energy and support their overall brain health with these nutrients. Users will need two capsules a day to get the benefits, though it doesn’t have the exact high dosages that other remedies do in this guide.

For 60 capsules, the total cost is $65. Plus, it comes with a money-back guarantee for the first six months of use.

Oweli Neuro


Oweli Neuro focuses mainly on helping users concentrate better and improving their mental function. With ingredients like huperzine A and phosphatidylserine, users get the calming effects that nootropics are known for. This formula also offers Bacopa Monnieri, B vitamins, inositol, and DMAE, giving users more calm energy to regain their focus.

All orders come with a money-back guarantee for the first 100 days, providing 60 capsules for $30.

ReMind Solution


ReMind Solution supports individuals who struggle to concentrate due to anxiety and stress. The formula is made with L-glutamine, phosphatidylserine, N-acetyl L-carnitine, huperzine A, vinpocetine, and gingko biloba. Along with reducing stress, users will find that this ingredient list is perfect for individuals who labor to focus and desire to improve their brain function.

Though this formula has a high price tag that doesn’t quite offer was lower-priced remedies do, the use of ReMind can still support the user’s cognition. Plus, if the user is unhappy with the results, they can get a refund with no questions asked.

To get a bottle with 30 capsules, the total cost is $69.

Brain Pill


Brain Pill focuses on reducing mental fatigue to help users focus and learn better. The remedy is made of vitamin B12, L-theanine, amino acids, and citicoline, assisting users with their memory and cognitive function. They’ll need to take two capsules a day to make a difference, but every order comes with a money-back guarantee for the first 67 days of use. With 13 nootropic supplements, users won’t have to worry about crashing or getting unpredictable side effects. However, there is no explanation of how much of these ingredients are used.

For 60 capsules, the total cost is $69.95.

ProMind Complex


ProMind Complex helps users improve their brain function, increase memory retention, and provide an overall boost to mental performance. Though there are many ingredients in this formula, the primary sources of support include vinpocetine, huperzine A, Bacopa Monnieri extract, L-glutamine, and phosphatidylserine.

Users will only need to take one capsule a day, which means that the 30-capsule bottle should last a month for $69.

Memory Hack


Memory Hack combines a few familiar ingredients, like Bacopa Monnieri. However, a few additions have widespread health benefits, including artichoke leaves, green tea, omega fatty acids, and more. The entire point of Memory Hack is to make information easier to recall while supporting a more balanced mood and higher energy levels. This formula can achieve all of these effects with two capsules each day.

For a 60-capsule bottle, the total cost is $69. It comes with a money-back guarantee that covers the first 180 days.



MemoSurge helps individuals who struggle with insomnia and anxiety improve their energy levels. It advertises itself to repair damage to the brain cells and reduce shrinkage that naturally occurs in the brain with age. With an assortment of ingredients seen many times on this list, users can expect improvements to their overall wellness with particular attention to MemoSurge.

A one-month supply, which is 30 capsules, costs $69.

Memo Defend


The final formula on this list, Memo Defend, provides a proprietary blend that accounts for the total 620mg dose. It includes garlic bulbs, hawthorn leaves, and olive leaves, but it is impossible to determine how many of these ingredients are inside. Still, research shows that using these ingredients can efficiently reduce brain fog and stimulate cognitive function. The star player of Memo Defend is vitamin B12, which the body already requires daily.

With two capsules a day, one bottle of 60 pills for $69 should be enough to get through the month.

How We Ranked The Top Nootropic Brain Booster Supplements

The hard part about choosing a nootropic formula is that these products seem to work similarly. Here’s a look at the criteria considered in selecting these formulas:

Science-Backed Ingredients

Based on clinical trials and studies, there are many ingredients in the nootropic space that positively affect cognition for consumers. The use of plant extracts, vitamins, minerals, and similar ingredients has a powerful effect on the body. The components included in these formulas had to be backed by legitimate science.

Effective Dosages

These formulas have to have the correct dose to be effective with the right ingredients. The formula couldn’t have too much of the element, and they couldn’t have such a minimal amount that it doesn’t matter at all.

Transparent Advertised Benefits

One of the difficulties with choosing a good nootropic supplement is that many brands exaggerate what they can do for consumers. Some say that the brain will become younger, while others promise impossible memory improvements. The top companies on the market today are the ones who are transparent about what they offer.

Proprietary Blends

Proprietary blends are tricky. While they can provide users with an exclusive and unique formula, the trouble is that they don’t show the amount of each ingredient. Even though companies focus on how positive proprietary blends can be, it is the easiest way to hide low amounts of active ingredients.

Doctor Formulated or Approved by a Medical Advisory Board

Whenever a supplement has a medical advisory board or medical professionals on staff, it is a good indication that consumers are getting a product worth the money. These experts create remedies that work, rather than being a team of marketers that simply want to improve their bottom line for a piece of this industry’s profit.

Manufacturer Reputation & Lab Testing

To ensure that a product is reliable, some companies put their formulas and ingredients through lab testing to show that it is worth purchasing. Manufacturers with a good reputation have established trust from customers with lab tests and other documentation. Companies that have put themselves through the wringer to prove that they perform well for consumers were a must, whether the brand had been around for long or short.

Customer Reviews

No one knows how a formula will work for them before they try it. However, good or bad experiences are often documented online through customer reviews. These reviews were considered in creating this list, showing consumers what other users have experienced before placing an order.

Price & Value

Regardless of the price tag, the formulas on this list had to be worth the money users would spend to buy it. Some people are willing to drop $200 each month to get the nootropic support possible, while others only want to spare $20 for a bit of pick-me-up. No matter what range the customer was willing to spend, every product provided equal value.

Clinical Trials & Peer-Reviewed Research

Most companies don’t spend the time or money to put their products through clinical trials because they are expensive and time-consuming. Getting products to market already takes a lot of time, but brands with excellent products don’t mind waiting.

Money-Back Guarantee

Any company that stands behind its product offers a money-back guarantee. They understand that every individual is different, and everyone doesn’t respond to their ingredients equally. Anyone unsatisfied can get a refund without having to explain themselves.

Scientific Support Behind the Benefits of Nootropic Supplements

With so many bold claims from supplement companies about the effectiveness of their nootropic formulas, understanding the truth in their advertising is essential. How do these remedies improve the mind? What scientific evidence can back it up?

As recently as a few years ago, the world of nootropic formulas was only just beginning. It is relatively easy to find research that others have already reviewed. Decades of research show that certain ingredients have a powerful effect on humans and animals, like Bacopa Monnieri, Ginkgo Biloba, and ashwagandha.

Bacopa Monnieri has gotten a lot more attention than other ingredients. It is found in many nootropic remedies, and a study from 2008 even backed up how it increases cognitive performance. Ginkgo Biloba is pretty similar, used in Chinese medicine for centuries. In 2001, researchers found that combining ginkgo Biloba with vinpocetine for two weeks improved their memory and response time.

Ashwagandha is a little different. Instead of directly impacting the brain’s performance, it acts as an adaptogen to improve relaxation and reduce stress. It can improve cardiovascular health, and a study as recently as 2016 found that this ingredient has “nootropic potential.”

L-theanine is a must for any formula that includes caffeine because it keeps the jittery sensation away. However, it keeps up the energy consumers want, ensuring that users won’t feel anxious or hyper when using these supplements.

Though all 33 formulas on this list are good options, the fact that Onnit Alpha Brain voluntarily put itself through clinical trials to show its effectiveness speaks volumes. According to the study, 63 participants experienced significant improvements to their memory when using the supplement for six weeks.

Ultimately, science has shown that today’s top products will improve mood, memory, cognition, and other aspects of brain health with the right ingredients. Always seek out ingredients and dosages that are proven to work.

Taking the Right Nootropic Dosages

There are no particular regulations on the market today to determine a single dosage that works for all products and all users. Every supplement is different. All of the formulas on this list come with complete instructions to ensure that users get the maximum benefits. Always follow the directions provided to eliminate the risk of adverse effects.

Consumers concerned about the dosages may want to speak with a medical professional to ensure their safety.

FAQs About Nootropic Supplementation

Q: What is a nootropic?

A: A nootropic refers to any supplement, drug, or food/drink that can help users improve cognitive function.

Q: What do nootropics do?

A: When an individual takes nootropics, they promote better brain function, improve memory, and promote better reactions in the brain. The primary benefits boasted are that these remedies can improve memory and function, though they can also improve energy levels.

Q: What’s the best nootropic?

A: All of the above products are superior formulas to help users.

Q: Are nootropics safe?

A: Yes. All of the formulas posted online are legally required to contain ingredients Generally Recognized as Safe (GRAS) by the FDA. As long as the company follows the recommended dosages, no side effects or unpredictable reactions will occur. However, if individuals take medication, they may want to speak with their doctor to ensure that their selected remedy is safe.

Q: Why should consumers take nootropic supplements?

A: Using nootropic supplements can help users who want a better memory, improved cognition, healthy brain cells, and more. Some of these remedies focus on one particular concern, like memory or focus, and include ingredients that specifically address them. Others provide overall healing and support.

Q: Who can get brain health benefits from a nootropic supplement?

A: Anyone can benefit. However, the people who have a lot of pressure from work or home to remember loads of information, like college students and entrepreneurs, seem to benefit the most. This brain stimulation can also help athletes, older adults, and individuals with a desire to think faster and more efficiently than the competition.

The Top 33 Nootropic Brain Booster Supplements Final Thoughts

All of the remedies listed above can help consumers learn what a nootropic can offer them. With more online products than ever before, the choice should be easy. This guide can help consumers determine the best formulas based on performance, ingredient profile, and what other customers have experienced. Try a top nootropic brain booster supplement today!

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